Is soybean bad for physical and mental health??

Is soybean bad for physical and mental health?

Soybean field in Zambia. Image: Hippopx.Com

According to a study, the most widely produced and consumed plant oil in the U.S. Could challenge not only obesity or diabetes, but also neurological damage – at least in mice

In South America, forests have been and continue to be cleared for the cultivation of soybeans. Almost 90 percent of soy production comes from genetically modified soybeans. Nevertheless, soy is considered a healthy and vegan food, which is often used as a substitute for meat or milk, because it contains a lot of vegetable protein as well as polyunsaturated fatty acids and important minerals. In the U.S., soybean oil is the most widely used edible oil, with a share of 90 percent.

Scientists at the University of California, Riverside, found back in 2015 that soybean oil is not good for mice. They had tested the effect of soybean oil in mice with that of hardened coconut fat and fructose, which is considered a fattening agent. They found that a diet high in soybean oil was worse for health than a diet high in coconut fat or fructose, because the mice gained much more weight – 25% than with coconut fat – and developed obesity, while the addition of fructose, i.E. Sugar, did not increase obesity, but actually decreased it. In addition, the mice fed soybean oil developed more fatty liver and insulin resistance and developed diabetes more frequently. In a 2017 study, they found that soybean oil, in which the amount of omega-6 linoleic acid was lowered, appeared to cause less obesity and insulin resistance.

Soybean oil affects the hypothalamus in mice

In a new study published in the journal Endocrinology, after further experiments with mice, they conclude that soybean may cause or be associated with neurological damage such as autism, dementia, Alzheimer’s disease, anxiety and depression. At least in mice whose RNA was sequenced to analyze altered gene expression, Sojaol affects the hypothalamus, which controls many processes, including metabolic processes, body temperature, fatigue, hunger, glucose homoostasis, etc., also releases neurohormones and is involved in behavioral and anxiety control.

The scientists had fed male mice with soyol with high content of linoleic acid, with reduced content of linoleic acid or with cocosol. Here, both forms of soybean had an effect on the hypothalamus, while the effects of cocosol were negligible. The main gene affected appears to be Oxt, which excretes oxytocin, which acts as both a hormone and a neuotransmitter, and is sometimes popularly known as the love hormone "love hormone" called. Oxytocin is involved in the control of food intake and energy expenditure, according to scientists. Both types of soy lower oxytocin levels. But they also affect about 100 other genes, which in turn may be linked to neurological damage. Thus, the gene Avp, which is associated with schizophrenia, is boosted, as well as Hcrt (depression, anxiety, pain) or Pcsk1n, which in conjunction with the protein ProSAAS indicates a risk of Alzheimer’s disease.

Of course, the study could not prove that soybean oil causes such damage, and it is by no means certain that it affects humans in the same way as it does male mice. It also had to be tested whether the effects on female mice are similar. More importantly, it has not been proven which components of soybean oil are responsible for the effect on the hypothalamus. Only linoleic acid should be excluded, since there is no difference between soybean oil with high or low content of linoleic acid, nor should it be stigmasterol, since its addition to the cocosol does not increase the oxt-RNA.

The scientists point out that their study challenges the commonly held assumption that saturated fatty acids are bad and unsaturated ones are good. Soybean oil contains polyunsaturated fatty acids, but whether this is good has yet to be proven. Cocosol, on the other hand, contains saturated acids, but this has little effect on gene expression in the hypothalamus. Co-author Poonamjot Deol advises in any case to reduce the consumption of soybean oil. Many soy products, such as soy milk and tofu, were found to contain only small amounts of the oil, but essential fatty acids and proteins, explains Frances Sladek, a toxicologist and cell biologist who led the study.

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